{"id":995,"date":"2023-05-10T16:39:48","date_gmt":"2023-05-10T14:39:48","guid":{"rendered":"https:\/\/www.linkidoc.fr\/blog\/2023\/05\/10\/la-capsule-fournit-du-courant-electrique-a-lestomac-pour-lappetit\/"},"modified":"2023-05-10T16:39:50","modified_gmt":"2023-05-10T14:39:50","slug":"la-capsule-fournit-du-courant-electrique-a-lestomac-pour-lappetit","status":"publish","type":"post","link":"https:\/\/www.linkidoc.fr\/blog\/2023\/05\/10\/la-capsule-fournit-du-courant-electrique-a-lestomac-pour-lappetit\/","title":{"rendered":"La capsule fournit du courant \u00e9lectrique \u00e0 l&rsquo;estomac pour l&rsquo;app\u00e9tit"},"content":{"rendered":"<div>\n<figure class=\"wp-block-image size-full\"><noscript><img loading=\"lazy\" decoding=\"async\" width=\"770\" height=\"502\" src=\"https:\/\/www.linkidoc.fr\/blog\/wp-content\/uploads\/2023\/05\/La-capsule-fournit-du-courant-electrique-a-lestomac-pour-lappetit.jpg\" alt=\"\" class=\"wp-image-1548525\"  \/><\/noscript><\/figure>\n<p>Des chercheurs du MIT ont mis au point une capsule \u00ab\u00a0\u00e9lectroceutique\u00a0\u00bb con\u00e7ue pour \u00eatre aval\u00e9e et qui d\u00e9livrera un petit courant \u00e9lectrique \u00e0 la paroi de l&rsquo;estomac.  L&rsquo;appareil contient une \u00e9lectrode externe qui s&rsquo;enroule autour de son ext\u00e9rieur et de petites rainures qui \u00e9loignent le liquide de l&rsquo;\u00e9lectrode et l&rsquo;aident \u00e0 entrer en contact avec la paroi de l&rsquo;estomac.  La technologie stimule les cellules endocrines de la muqueuse de l&rsquo;estomac pour qu&rsquo;elles s\u00e9cr\u00e8tent davantage une hormone appel\u00e9e ghr\u00e9line, qui stimule l&rsquo;app\u00e9tit et r\u00e9duit les naus\u00e9es.  Les chercheurs esp\u00e8rent que l&rsquo;appareil pourrait aider les patients souffrant de troubles de l&rsquo;alimentation ou de conditions telles que la cachexie, une condition d\u00e9bilitante qui peut survenir chez les patients canc\u00e9reux.<\/p>\n<p>Le concept de fourniture d&rsquo;\u00e9lectricit\u00e9 \u00e0 l&rsquo;estomac pour aider \u00e0 r\u00e9soudre les probl\u00e8mes gastro-intestinaux a d&rsquo;abord \u00e9t\u00e9 test\u00e9 chez des patients atteints de gastropar\u00e9sie qui pr\u00e9sentent une motilit\u00e9 gastro-intestinale lente, dans l&rsquo;espoir que cela am\u00e9liorerait les contractions de l&rsquo;estomac.  Un dispositif semblable \u00e0 un stimulateur cardiaque implant\u00e9 dans l&rsquo;estomac a aid\u00e9 \u00e0 am\u00e9liorer les sympt\u00f4mes, mais n&rsquo;a pas fait grand-chose pour augmenter la motilit\u00e9.  Par cons\u00e9quent, ces chercheurs ont \u00e9mis l&rsquo;hypoth\u00e8se que l&rsquo;\u00e9lectricit\u00e9 avait un effet sur l&rsquo;app\u00e9tit en stimulant les cellules endocrines de l&rsquo;estomac \u00e0 s\u00e9cr\u00e9ter plus de ghr\u00e9line.<\/p>\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"466\" height=\"311\" data-lazy-type=\"image\" src=\"https:\/\/www.linkidoc.fr\/blog\/wp-content\/uploads\/2023\/05\/1683729587_238_La-capsule-fournit-du-courant-electrique-a-lestomac-pour-lappetit.jpg\" alt=\"\" class=\"lazy lazy-hidden wp-image-1548526\"  data-lazy-\/><noscript><img decoding=\"async\" loading=\"lazy\" width=\"466\" height=\"311\" src=\"https:\/\/www.linkidoc.fr\/blog\/wp-content\/uploads\/2023\/05\/1683729587_238_La-capsule-fournit-du-courant-electrique-a-lestomac-pour-lappetit.jpg\" alt=\"\" class=\"wp-image-1548526\"  \/><\/noscript><\/figure>\n<\/div>\n<p>Ils ont test\u00e9 leur hypoth\u00e8se sur des animaux, constatant qu&rsquo;un petit courant \u00e9lectrique dans l&rsquo;estomac augmentait effectivement les niveaux de ghr\u00e9line.  Pour traduire cela en quelque chose qui avait un potentiel clinique, ils ont maintenant d\u00e9velopp\u00e9 cette capsule \u00e9lectroceutique qui peut \u00eatre simplement aval\u00e9e, \u00e9vitant ainsi la n\u00e9cessit\u00e9 d&rsquo;une intervention chirurgicale.<!-- ASYNC UAT M - 300x250(t,r) - --><\/p>\n<p><!-- END ASYNC UAT M - 300x250(t,r) --><\/p>\n<p>\u00ab\u00a0Cette \u00e9tude aide \u00e0 \u00e9tablir la stimulation \u00e9lectrique par des \u00e9lectroceutiques ing\u00e9rables comme mode de d\u00e9clenchement de la lib\u00e9ration d&rsquo;hormones via le tractus gastro-intestinal\u00a0\u00bb, a d\u00e9clar\u00e9 Giovanni Traverso, un chercheur impliqu\u00e9 dans l&rsquo;\u00e9tude.  \u00ab\u00a0Nous montrons un exemple de la fa\u00e7on dont nous sommes capables de nous engager avec la muqueuse de l&rsquo;estomac et de lib\u00e9rer des hormones, et nous pr\u00e9voyons que cela pourrait \u00eatre utilis\u00e9 dans d&rsquo;autres sites du tractus gastro-intestinal que nous n&rsquo;avons pas explor\u00e9s ici.\u00a0\u00bb<\/p>\n<p>L&rsquo;\u00e9quipe du MIT a con\u00e7u la capsule pour un contact maximal avec la paroi de l&rsquo;estomac.  Les fluides dans l&rsquo;estomac pourraient interf\u00e9rer avec cela, de sorte que la capsule contient de petites rainures avec un rev\u00eatement hydrophile qui \u00e9loignent le fluide de l&rsquo;\u00e9lectrode.  Le concept a \u00e9t\u00e9 inspir\u00e9 par la peau du l\u00e9zard \u00e9pineux australien, qui contient de minuscules rainures qui aident \u00e0 attirer l&rsquo;eau vers la bouche du l\u00e9zard.<\/p>\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"770\" height=\"508\" data-lazy-type=\"image\" src=\"https:\/\/www.linkidoc.fr\/blog\/wp-content\/uploads\/2023\/05\/1683729588_787_La-capsule-fournit-du-courant-electrique-a-lestomac-pour-lappetit.jpg\" alt=\"\" class=\"lazy lazy-hidden wp-image-1548528\"  data-lazy-\/><noscript><img decoding=\"async\" loading=\"lazy\" width=\"770\" height=\"508\" src=\"https:\/\/www.linkidoc.fr\/blog\/wp-content\/uploads\/2023\/05\/1683729588_787_La-capsule-fournit-du-courant-electrique-a-lestomac-pour-lappetit.jpg\" alt=\"\" class=\"wp-image-1548528\"  \/><\/noscript><\/figure>\n<p>\u00ab\u00a0Nous nous sommes inspir\u00e9s de cela pour incorporer des textures et des motifs de surface \u00e0 l&rsquo;ext\u00e9rieur de cette capsule\u00a0\u00bb, a d\u00e9clar\u00e9 James McRae, un autre chercheur impliqu\u00e9 dans le projet.  \u00ab\u00a0Cette surface peut g\u00e9rer le fluide qui pourrait potentiellement emp\u00eacher les \u00e9lectrodes de toucher les tissus de l&rsquo;estomac, de sorte qu&rsquo;elle peut fournir une stimulation \u00e9lectrique de mani\u00e8re fiable.\u00a0\u00bb<\/p>\n<p>Voici une vid\u00e9o du MIT pr\u00e9sentant la technologie\u00a0:<\/p>\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\">\n<div class=\"wp-block-embed__wrapper\">\n<img decoding=\"async\" class=\"lazy lazy-hidden\" data-lazy-type=\"iframe\" src=\"&lt;iframe loading=&quot;lazy&quot; title=&quot;FLASH - Full Length&quot; width=&quot;770&quot; height=&quot;433&quot; bad-src=&quot;https:\/\/www.youtube.com\/embed\/Tybn9nbwfZc?feature=oembed&quot; frameborder=&quot;0&quot; allow=&quot;accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share&quot; allowfullscreen&gt;&lt;\/iframe&gt;\" alt=\"\"\/><noscript><iframe loading=\"lazy\" title=\"FLASH - Full Length\" width=\"1200\" height=\"675\" src=\"https:\/\/www.youtube.com\/embed\/Tybn9nbwfZc?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/noscript>\n<\/div>\n<\/figure>\n<p>\u00c9tudier dans la revue <em>Robotique scientifique<\/em>: Capsules \u00e9lectroceutiques bioinspir\u00e9es et ing\u00e9rables pour la modulation hormonale r\u00e9gulatrice de la faim<\/p>\n<p>Flashback\u00a0: un capteur ing\u00e9rable r\u00e9v\u00e8le la motilit\u00e9 gastrique<\/p>\n<p>Via : MIT<\/p>\n<p><!--TrendMD v2.4.8--><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Des chercheurs du MIT ont mis au point une capsule \u00ab\u00a0\u00e9lectroceutique\u00a0\u00bb con\u00e7ue pour \u00eatre aval\u00e9e et qui d\u00e9livrera un petit<\/p>\n","protected":false},"author":1,"featured_media":996,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[1329,1331,1255,1330,1333,1332,5],"class_list":["post-995","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-non-classe","tag-capsule","tag-courant","tag-electrique","tag-fournit","tag-lappetit","tag-lestomac","tag-pour","generate-columns","tablet-grid-50","mobile-grid-100","grid-parent","grid-50"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - 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